Microwave-assisted efficient one-pot synthesis of N2-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines

Moustafa Sherief Moustafa; Ramadan Ahmed Mekheimer; Saleh Mohammed Al-Mousawi; Mohamed Abd-Elmonem; Hesham El-Zorba; Afaf Mohamed Abdel Hameed; Tahany Mahmoud Mohamed; Kamal Usef Sadek

doi:10.3762/BJOC.16.142

Microwave-assisted efficient one-pot synthesis of N²-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines

Moustafa Sherief Moustafa
, Ramadan Ahmed Mekheimer
, Saleh Mohammed Al-Mousawi
, Mohamed Abd-Elmonem
, Hesham El-Zorba
, Afaf Mohamed Abdel Hameed
, Tahany Mahmoud Mohamed
, Kamal Usef Sadek

Kuwait University

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

An efficient one-pot synthesis of N²-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of the obtained products.

Original language	English
Pages (from-to)	1706-1712
Number of pages	7
Journal	Beilstein Journal of Organic Chemistry
Volume	16
DOIs	https://doi.org/10.3762/BJOC.16.142
State	Published - 16 Jul 2020

Keywords

3
4-diamines; one-pot synthesis; X-ray crystallography
5-triazine-2
Microwave irradiation; N-(tetrazol-5-yl)-6-aryl/heteroaryl-1

Funding Agency

Kuwait Foundation for the Advancement of Sciences

Access to Document

10.3762/BJOC.16.142

Cite this

@article{6f0023b863a846c89260e17f5cab813c,

title = "Microwave-assisted efficient one-pot synthesis of N2-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines",

abstract = "An efficient one-pot synthesis of N2-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of the obtained products.",

keywords = "3, 4-diamines; one-pot synthesis; X-ray crystallography, 5-triazine-2, Microwave irradiation; N-(tetrazol-5-yl)-6-aryl/heteroaryl-1",

author = "Moustafa, \{Moustafa Sherief\} and Mekheimer, \{Ramadan Ahmed\} and Al-Mousawi, \{Saleh Mohammed\} and Mohamed Abd-Elmonem and Hesham El-Zorba and Hameed, \{Afaf Mohamed Abdel\} and Mohamed, \{Tahany Mahmoud\} and Sadek, \{Kamal Usef\}",

note = "Publisher Copyright: {\textcopyright} 2020 Moustafa et al.;",

year = "2020",

month = jul,

day = "16",

doi = "10.3762/BJOC.16.142",

language = "English",

volume = "16",

pages = "1706--1712",

journal = "Beilstein Journal of Organic Chemistry",

issn = "1860-5397",

publisher = "Beilstein-Institut Zur Forderung der Chemischen Wissenschaften",

}

TY - JOUR

T1 - Microwave-assisted efficient one-pot synthesis of N2-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines

AU - Moustafa, Moustafa Sherief

AU - Mekheimer, Ramadan Ahmed

AU - Al-Mousawi, Saleh Mohammed

AU - Abd-Elmonem, Mohamed

AU - El-Zorba, Hesham

AU - Hameed, Afaf Mohamed Abdel

AU - Mohamed, Tahany Mahmoud

AU - Sadek, Kamal Usef

PY - 2020/7/16

Y1 - 2020/7/16

N2 - An efficient one-pot synthesis of N2-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of the obtained products.

AB - An efficient one-pot synthesis of N2-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of the obtained products.

KW - 3

KW - 4-diamines; one-pot synthesis; X-ray crystallography

KW - 5-triazine-2

KW - Microwave irradiation; N-(tetrazol-5-yl)-6-aryl/heteroaryl-1

UR - https://www.scopus.com/pages/publications/85108265601

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DO - 10.3762/BJOC.16.142

M3 - Article

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VL - 16

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EP - 1712

JO - Beilstein Journal of Organic Chemistry

JF - Beilstein Journal of Organic Chemistry

ER -